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1

Water-soluble prodrugs of an Aurora kinase inhibitor

Johan D. Oslob, Stacey A. Heumann, Chul H. Yu, Darin A. Allen, Subramanian Baskaran, Minna Bui, Erlie Delarosa, Amy D. Fung, Ahmad Hashash, Jonathan Hau, Sheryl Ivy, Jeffrey W. Jacobs, Willard Lew, Ja

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 426 KB

english, 2009

2

Oxygen as Oxidant in Palladium-Catalyzed Inter- and Intramolecular Coupling Reactions

Helena Hagelin, Johan D. Oslob, Björn Åkermark

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 94 KB

english, 1999

3

ChemInform Abstract: Asymmetric Synthesis of (-)-Anatoxin-a via an Asymmetric Cyclization Using a New Ligand for Pd-Catalyzed Alkylations.

Barry M. Trost, Johan D. Oslob

Journal:

Year:

1999

File:

PDF, 30 KB

1999

4

Identification of Nonpeptidic Small-Molecule Inhibitors of Interleukin-2.

Nathan D. Waal, Wenjin Yang, Johan D. Oslob, Michelle R. Arkin, Jennifer Hyde, Wanli Lu, Robert S. McDowell, Chul H. Yu, Brian C. Raimundo

Journal:

Year:

2005

File:

PDF, 11 KB

2005

5

Catalytic oxidative aromatic cyclizations with palladium

Björn Åkermark, Johan D. Oslob, Ulrich Heuschert

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 115 KB

english, 1995

6

Discovery of a potent and selective Aurora kinase inhibitor

Johan D. Oslob, Michael J. Romanowski, Darin A. Allen, Subramanian Baskaran, Minna Bui, Robert A. Elling, William M. Flanagan, Amy D. Fung, Emily J. Hanan, Shannon Harris, Stacey A. Heumann, Ute Hoch,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 459 KB

english, 2008

7

Identification of nonpeptidic small-molecule inhibitors of interleukin-2

Nathan D. Waal, Wenjin Yang, Johan D. Oslob, Michelle R. Arkin, Jennifer Hyde, Wanli Lu, Robert S. McDowell, Chul H. Yu, Brian C. Raimundo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 227 KB

english, 2005

8

Structure–activity relationship (SAR) of the α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists

Min Zhong, Emily J. Hanan, Wang Shen, Minna Bui, Michelle R. Arkin, Kenneth J. Barr, Marc J. Evanchik, Ute Hoch, Jennifer Hyde, Jose R. Martell, Johan D. Oslob, Kumar Paulvannan, Saileta Prabhu, Jeffr

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 349 KB

english, 2011

9

Asymmetric Synthesis of (−)-Anatoxin-a via an Asymmetric Cyclization Using a New Ligand for Pd-Catalyzed Alkylations

Trost, Barry M., Oslob, Johan D.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 196 KB

english, 1999

10

Tethering in early target assessment

Johan D Oslob, Daniel A Erlanson

Journal:

Drug Discovery Today: TARGETS

Year:

2004

Language:

english

File:

PDF, 795 KB

english, 2004

11

Integrating Fragment Assembly and Biophysical Methods in the Chemical Advancement of Small-Molecule Antagonists of IL-2: An Approach for Inhibiting Protein−Protein Interactions †

Raimundo, Brian C., Oslob, Johan D., Braisted, Andrew C., Hyde, Jennifer, McDowell, Robert S., Randal, Mike, Waal, Nathan D., Wilkinson, Jennifer, Yu, Chul H., Arkin, Michelle R.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 554 KB

english, 2004

12

Imidazopyridine-Based Fatty Acid Synthase Inhibitors That Show Anti-HCV Activity and in Vivo Target Modulation

Oslob, Johan D., Johnson, Russell J., Cai, Haiying, Feng, Shirley Q., Hu, Lily, Kosaka, Yuko, Lai, Julie, Sivaraja, Mohanram, Tep, Samnang, Yang, Hanbiao, Zaharia, Cristiana A., Evanchik, Marc J., McD

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 722 KB

english, 2013

13

Allylic Carboxylations and Lactonization Using Benzoquinone and Hydrogen Peroxide or tert-Butyl Hydroperoxide as Oxidants

Aakermark, Bjoern, Larsson, E. Magnus, Oslob, Johan D.

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 739 KB

english, 1994

14

Molecular Mechanics Predictions and Experimental Testing of Asymmetric Palladium-Catalyzed Allylation Reactions Using New Chiral Phenanthroline Ligands

Peña-Cabrera, Eduardo, Norrby, Per-Ola, Sjögren, Magnus, Vitagliano, Aldo, De Felice, Vincenzo, Oslob, Johan, Ishii, Shingo, O'Neill, David, Åkermark, Björn, Helquist, Paul

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 731 KB

english, 1996

15

Discovery of a Potent Small Molecule IL-2 Inhibitor through Fragment Assembly

Braisted, Andrew C., Oslob, Johan D., Delano, Warren L., Hyde, Jennifer, McDowell, Robert S., Waal, Nathan, Yu, Chul, Arkin, Michelle R., Raimundo, Brian C.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 72 KB

english, 2003

16

Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye

Zhong, Min, Gadek, Thomas R., Bui, Minna, Shen, Wang, Burnier, John, Barr, Kenneth J., Hanan, Emily J., Oslob, Johan D., Yu, Chul H., Zhu, Jiang, Arkin, Michelle R., Evanchik, Marc J., Flanagan, W. Mi

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 278 KB

english, 2012

17

Modulation of the Cardiac Sarcomere by a Small Molecule Agent MYK0000461: A Potential Therapeutic for the Treatment of Genetic Hypertrophic Cardiomyopathies

Rodriguez, Hector M., Whitman-Cox, Stephanie, Kawas, Raja, Song, Yonghong, Sran, Arvinder, Oslob, Johan

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

18

Cardiac Selective Modulator of Human Myosin for the Treatment of Genetic Hypertrophic Cardiomyopathy

Ghermazien, Haben T., Song, Yonghong, Willits, Christopher P., Sran, Arvinder S., Anderson, Robert L., Rodriguez, Hector M., Oslob, Johan

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 62 KB

english, 2014

19

Steric Influences on the Selectivity in Palladium-Catalyzed Allylation

Oslob, Johan D., Åkermark, Björn, Helquist, Paul, Norrby, Per-Ola

Journal:

Organometallics

Year:

1997

Language:

english

File:

PDF, 210 KB

english, 1997

20

Conformations of (.eta.3-Cyclohexenyl)palladium Systems. A Molecular Mechanics (MM2) Study

Aakermark, Bjoern, Oslob, Johan D., Norrby, Per-Ola

Journal:

Organometallics

Year:

1995

Language:

english

File:

PDF, 676 KB

english, 1995